Rey Mysterio looks to hold on to the WWE Championship for more than just one night as he goes one-on-one with John Cena in a thrilling Raw main event: Courtesy of WWE Network.

John Cena and Rey Mysterio went one-on-one for the very first time on this day in 2003!

WWE travels to Iraq to and puts on a show for the troops with a mega main event. John Cena, Batista & Rey Mysterio clash with Randy Orton, Chris Jericho & Big Show.

The high-flying Rey Mysterio clashes with the up-and-coming sensation John Cena.

May 26, 2018 · Watch Rey Mysterio vs. John Cena- SmackDown, November 6, 2003 - Barbarabennettdm on Dailymotion

Nov 6, 2003 · Relive the FIRST-EVER battle between John Cena and Rey Mysterio from WWE SmackDown! #SummerOfCena

Nov 6, 2017 · No strategy was off limits for John Cena when he battled Rey Mysterio on this day in 2003!

Aug 16, 2021 · Rey Mysterio vs. John Cena: SmackDown, Nov. 6, 2003 (Full Match)

Sep 21, 2024 · With the WWE Champion having walked out on the company, Rey Mysterio and The Miz fought in the opener of the July 25th Raw to crown a new champion. Mysterio would end up winning that bout and would accept a challenge from John Cena to defend it that same night.

Jul 25, 2011 · John Cena vs. Rey Mysterio MatchOverview Other Matches Ratings Comments