Helicases are dynamic enzymes that play essential roles in DNA and RNA metabolism, transcription, repair, and recombination and are often dysregulated in human diseases. In addition, helicases are ...

However, abnormal helicase expression has been associated with immune response, cancer, and intellectual disability in humans. Superfamily II (SFII) is one of the largest and most diverse of the ...

They play various regulatory roles in many biological processes. It is commonly agreed that G4 unwinding helicases play key roles in G4 metabolism and function, and these processes are closely related ...

Applying this approach to N-acetyltransferases, P-loop GTPases, RNA helicases, synaptojanin-superfamily phosphatases and nucleases, and thymine/uracil DNA glycosylases yielded results congruent with ...

A large group of helicases, known as superfamily 1 and 2, are involved in virtually all aspects of the control of RNA and DNA structure. All of these helicases contain a region called the ‘helicase ...