The researchers noted that additional studies they’ve conducted have shown that the simultaneous targeting of glucose and glutamine availability, using KMT and the a pan-glutaminase inhibitor—known as ...
Engineering Research Center of Ministry of Education on Food Synthetic Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China Science Center for Future Foods, Jiangnan ...
Inhibition of glutaminase (GLS) in lung tumor cells results in glutathione (GSH) depletion and tumor cell-specific cytotoxicity. Dr. Boysen utilizes advanced therapy approaches, such as combination ...
Examples of metabolite ratios that may serve as readouts for comparative enzyme activities include glutamine to glutamate for glutaminase (GLS), aspartate to asparagine for asparagine synthase (ASNS), ...
CB-839, an oral glutaminase inhibitor, showed encouraging safety and tolerability results in a phase 1 study conducted in patients with advanced and/or treatment-refractory solid tumors, including ...
The combination of the glutaminase inhibitor CB-839 and 5-fluorouracil induces IL-8 expression in PiK3CA-mutated CRC cells, attracting neutrophils to tumor tissues, inducing NET formation and ...
Using protein-glutaminase treatment to make veggie-burgers more moist Dec 7, 2023 Some plant-based steaks and cold cuts are lacking in protein, researchers find ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Cerebral dysfunctions give rise to a wide range of neurological diseases due to the ...
Department of Pediatrics, Pediatric Intensive Care Unit, Shengjing Hospital of China Medical University, Shenyang (N.Y., Y.-P.L., R.W., Y.-H.Y., T.Z., X.-R.Y., Y.-F.X ...
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