First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA ...

How does the cell protect these strands from damage? How would you identify the protein that serves as a connector between DNA helicase and pol-a/primase? A simple yet often effective approach is ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a ...