First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a ...

Institute for Genomic Biology professor Sua Myong and physics professor Taekjip Ha led a team that discovered the mechanism by which the hepatitis C helicase unwinds DNA and RNA for replication.