Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands. As the helicase moves along the DNA ...

In H1, the company hopes to initiate a first-in-human (FIH) trial of its candidate ABI-5366, a helicase-primase inhibitor targeting patients with HSV2, specifically recurrent genital herpes.