PEOPLE confirms that Bush will join the medical drama in the Nov. 7 episode as Dr. Cass Beckman Sophia Bush is ready to get her scrubs back on. The actress, 42, will be joining Grey's Anatomy for the hit show's 21st season,

One Tree Hill alumna Sophia Bush has been tapped for a recurring role on ABC's Grey's Anatomy, playing Dr. Cass Beckman, a trauma surgeon.

Sophia Bush is scrubbing into Grey’s Anatomy! Find out who she’s playing in the hit drama here! Grey’s Anatomy has a great habit of bringing in some good actors for recurring roles that often turn into regulars.