These are produced from longer dsRNA by the cellular type III endoRNase Dicer. One strand or both strands of the siRNA become(s) incorporated into a large protein complex known as the 'RNA-induced ...

Jeang, Yamina Bennasser, and colleagues characterized a sequence in the HIV-1 genome that encodes a rare siRNA precursor: a short hairpin RNA (shRNA) that is processed by the Dicer (or by a Dicer-like ...