Eisenmenger syndrome is an advanced form of pulmonary arterial ... 5), was designed to confirm the drug's safety and efficacy. These findings show that bosentan can improve the hemodynamics ...
As an orally available inhibitor of endothelin-1, which has been implicated in the pathogenesis of vascular disease in systemic sclerosis (SSc), bosentan is widely used as first-line therapy for ...
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