Erucamide, a fatty acid amide produced by plants, has antibacterial properties and may be useful as an ecofriendly pesticide ...
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AI-Powered Enzyme Engineering Speeds Up Drug Synthesisand functional assays to efficiently map protein sequence-function relationships. Applied to amide synthetases, it evaluated 1217 variants and identified optimized enzymes for pharmaceutical ...
The blended amide-ketide backbone that the reaction yields ... resistant to cleavage by proteases, and embed rings in protein backbones. Wilfred van der Donk, a chemist at the University of ...
Amide synthases catalyse the formation of macrolactam ... Understanding the structural dynamics and protein-substrate interactions for the bacterial cytochrome P450BM3, a haem-containing enzyme ...
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