Combining NFL picks and building NFL parlays is a common way to try to make a quick buck, but nailing NFL score predictions can be highly profitable. NFL matchups, potential game flow and NFL betting trends should all be taken into consideration before locking in Week 7 NFL game picks.

There are 15 games on the NFL slate in Week 7, beginning with the Denver Broncos and New Orleans Saints on Thursday, then continuing Sunday for the third and final London game of the season, which has the Jacksonville Jaguars hosting the New England Patriots at Wembley Stadium.

Sportsbooks give the New York Jets (2-4) a slight chance to break their one-game losing streak, as they are favored by 2 points in a matchup against the Pittsburgh Steelers (4-2) on Sunday,

SportsLine's Model reveals its top Week 7 NFL picks, NFL best bets, NFL parlay picks, NFL parlay card, NFL predictions, and 25-1 football parlay

But almost all the bets in this column will be based on the outputs of models built by me, or occasionally my colleagues at ESPN Analytics. A less efficient market. NFL sides and totals are voluminous markets,

The Kansas City Chiefs (5-0) will look to keep their five-game winning streak alive as they are 1.5-point underdogs against the San Francisco 49ers (3-3) on Sunday, October 20, 2024 at

Will the Patriots eclipse their win 4.5 season win total? According to FOX Sports betting analyst Will Hill, they'll miss the mark. Find out why he's wagering the Under.

An NFC North showdown for first place in the division and the NFC headlines this week’s schedule. Plus, a rematch of a pair of Super Bowls.